GenuinePurity™ Fisetin

Made With A Clinically Studied Dose

Importantly, no adverse effects of fisetin have been reported, even when given at high doses. Thus, our results suggest that supplementation … with this safe, natural product could improve healthy aging, even in elderly individuals.”

The research agrees - supplementing with fisetin is well tolerated. And preliminary findings hint lower amounts may outperform higher doses. That's why our formula is made with a clinically studied dose of 150 mg.

One of the most astounding animal trials saw fisetin swiftly reducing "zombie-like" cells in fat tissues of youthful mice within just 5 days.

Optimized For Maximum Effectiveness With Liposomal Encapsulation Technology

Our state-of-the-art formula is made with a liposomal encapsulation technology that helps increase the effectiveness of fisetin in three distinct ways:

• #1 Forms a safeguarding "shield," protecting the fisetin from stomach acids and preserving the integrity
• #2 Amplifies solubility, simplifying the absorption process for the fisetin to enter your bloodstream effortlessly
• #3 Elevates cellular uptake by facilitating liposomal fusion with cell membranes, ensuring the fisetin is delivered directly to your cells

A Powerful Antioxidant for Defending Against Oxidative Stress & Cellular Damage

[Fisetin] acts as an antioxidant … maintains mitochondrial function in the presence of oxidative stress…”

- Antioxidant & Redox Signaling

Fisetin is a flavonoid that exhibits potent antioxidant properties and protects the cells against oxidative stress”

- Frontiers

Antioxidant Capabilities:

Fisetin is a powerful antioxidant that can neutralize reactive oxygen species and free radicals. Their overproduction contributes to oxidative stress, which damages cells. By limiting these threats, fisetin counters cellular damage.

Cellular Defense:

Fisetin may spark various intrinsic defenses, switching on antioxidant enzymes working to preserve wellness. By boosting their activities, fisetin supports the body's power to withstand oxidative turbulence and maintain cellular security.

Mitochondrial Safeguarding:

As energy hubs within cells, mitochondria are prone to oxidative harm. Research suggests fisetin fortifies mitochondria from oxidative stresses, allowing their functions and structures to remain sound. This preserves the cellular infrastructure for sustained well-being.

A Natural Way to Reduce Inflammation

Recent clinical trials have reported that fisetin (100 mg) supplements taken for seven consecutive weeks significantly reduced inflammation markers”

- International Journal of Molecular Sciences

[Fisetin] inhibits the production of pro-inflammatory cytokines and enzymes, which can help to reduce inflammation in the body”

- ScienceDirect

Inflammatory Mediator Mitigation:

Research shows fisetin suppresses generation and function of various pro-inflammatory players such as cytokines and chemokines, key actors in inflammation.

Modulated Pathway Interference:

Fisetin hinders specific chains linked to inflammation, reportedly obstructing activation of nuclear factor-kappa B. This conductor greatly steers inflammatory responses. Because of this, fisetin could regulate the inflammatory cascade.

Enzyme Expression Edging:

Reports indicate fisetin restricts enzymes involved in synthesizing pro-inflammatory prostaglandins and leukotrienes, like cyclooxygenase-2 and lipoxygenase. Taming these enzymes likely modulates the inflammatory effect.

Supports Cardiovascular Health

…Fisetin treatment improved cardiac function…”

- International Heart Journal

Additionally, fisetin attenuated LPS-induced mortality and abnormalities in zebrafish larvae and normalized the heart rate.”

- Scientific Reports

Lipid Lifting:

Research explores fisetin's potential to positively shape lipid profiles. Some findings suggest it reduces totals for cholesterol, unhealthy LDL and triglycerides while elevating heart-shielding HDL. Cultivating desirable lipid levels fortifies the cardiovascular system.

Vessel Vasodilation:

Reports show fisetin wields vasodilating ways, relaxing arteries to boost circulation and moderate blood pressure—further guarding cardiovascular function with less strain on the heart.

Anti-Clotting Activity:

Fisetin's antiplatelet aptitudes have been scrutinized as it may thwart overzealous clumping of fibrinogens. Excessive congregation can instigate thrombus formation linked to unwanted cardiovascular outcomes.

Enhances Healthspan and Extends Lifespan

Fisetin is a senotherapeutic that extends health and lifespan”

- Mayo Clinic

Fisetin… has been found to have a significant positive effect on the health and longevity of older mice.”

- Plant Foods for Human Nutrition

Senescent Slayer:

Fisetin shows promise as a senolytic skilled at selectively eliminating aged yet metabolically active cells no longer duplicating. As they can disturb tissues and spike inflammation, clearing these senescent cells through fisetin may optimize wellness and extend lifespan.

Cellular Champion:

Research probes fisetin's capacity to bolster mitochondrial functions and cell health crucial to avoided decline linked to maturing. Supporting mitochondrial integrity potentially furthers longevity.

DNA Defender:

Oxidative turmoil can compromise genetic coding. Fisetin has been eyed for abilities to aid DNA's mending motifs, critical to maintaining chromosomal security and staving off mutation buildups tied to health issues.

How Fisetin Works As A Senolytic

Fisetin reduced senescence in a subset of cells in murine and human adipose tissue”

Senescent cells, nicknamed “zombie” cells, are dysfunctional cells that don’t die. Accumulating over several years, their presence corrupts genetic operations, damages DNA and propels the maturing pattern.

Fisetin is a senolytic, selectively targeting these cells for termination. In fact, fisetin is the planet's most powerful senolytic. Findings link the removal of senescent cells to improved wellness and extended lifespan.

Proudly Made In The USA, In cGMP-Certified Facilities

GenuinePurity™ Fisetin is made in cGMP-certified facilities, right here in the USA, to ensure the highest quality possible. This means we follow the highest manufacturing standards so you can feel confident every time you order our formulas.